Helmut Roniger and Jennifer Jacobs

Prophylaxis against Leptospirosis using a nosode: Can this large cohort study serve as a model for future replications?

Homeopathy, 2010, 99 (3), 153-155

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This issue of the journal features an historic cohort study of homeoprophylaxis using Leptospirosis nosode, the scale is huge: it involved the entire population of Cuba.1 G. Bracho, E. Varela and R. Fernandez et al., Large-scale application of highly diluted bacteria for Leptospirosis epidemic control, Homp 99 (3) (2010), pp. 156–166. Article | PDF (409 K) 1 This should become a catalyst for future research in clinical homeopathy. The methodology is straightforward, making replication relatively easy, and the use of a nosode eliminates the interference of ideological prescribing variations. Furthermore, the size of the population treated and the dramatic decrease in disease incidence compared to previous years make it difficult to dismiss these results as spurious or occurring by chance.Homeoprophylaxis with nosodes has been practised for many years but is not typically used by practitioners of Classical Homeopathy. Similar to a conventional vaccine, a homeopathic nosode is made by taking an inactivated disease agent or product and subjecting it to the processes of dilution and succussion typical in the preparation of homeopathic medicines. The scientific evidence for the prevention of disease using nosodes thus far is sparse, as referenced in the article. It consists mainly of observational studies, one controlled clinical human study using Meningococcinum which was poorly reported,2 two controlled animal studies on different organisms[3] and [4] and a plant based model.5

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